I've come across this question on Quora where it's likely to be forgotten.
Unlike other disabilities that are often considered in design, dyslexia has many forms. As a result, the guidelines can't be just one-liner, such as "use X font" or "make sure contrast ratio is Y".
The best answer must cite hard evidence.
Answer
There a number of one pagers that talk about how you might design a site for users with dyslexia, I would recommend this three part series Designing for Dyslexics as a solid foundation:
- Part 1 (Definition of dyslexia, population size, implications/effects)
- Part 2 (Lower color contrast & visually impaired users)
- Part 3 (Typography, layouts, language style, information architecture, screen readers)
Here is a style guide from the British Dyslexia Association.
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